2017  2016   2015   2014   2013   2012     2011     2010     2009     2008     2007     2006     2005     2004     2003 


2017

  • Brüser AZimmermann A, Crews BC, Sliwoski G, Meiler J, König GM, Kostenis E, Lede V, Marnett LJ, Schöneberg T. Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6. Sci Rep. 2017; 7: 2380.
  • Demberg LM, Winkler J, Wilde C, Simon KU, Schön J, Rothemund S, Schöneberg T, Prömel S, Liebscher I. Activation of adhesion G protein-coupled receptors: agonist specificity of Stachel sequence-derived peptides. J Biol Chem. 2017; pii: jbc.M116.763656. [Epub ahead of print].
  • Lede V, Meusel A, Garten A, Popkova Y, Penke M, Franke C, Ricken A, Schulz A, Kiess W, Huster D, Schöneberg T, Schiller J. Altered hepatic lipid metabolism in mice lacking both the melanocortin type 4 receptor and low density lipoprotein receptor. PLoS One. 2017 Feb 16;12(2):e0172000. doi: 10.1371/journal.pone.0172000. [Epub ahead of print]. 
  • Le Duc D, Schulz A, Lede V, Schulze A, Thor D, Brüser A, Schöneberg T. P2Y Receptors in Immune Response and Inflammation. Adv Immunol. 2017;136:85-121.
  • Lin HH, Hsiao CC, Pabst C, Hébert J, Schöneberg T, Hamann J. Adhesion GPCRs in Regulating Immune Responses and Inflammation. Adv Immunol. 2017;136:163-201.
  • Merkwitz C, Blaschuk O, Winkler J, Schulz A, Prömel S, Ricken AM. Advantages and Limitations of Salmon-Gal/Tetrazolium Salt Histochemistry for the Detection of LacZ Reporter Gene Activity in Murine Epithelial Tissue. J Histochem Cytochem. 2017; 65: 197-206.
  • Scholz N, Guan C, Nieberler M, Grotemeyer A, Maiellaro I, Gao S, Beck S, Pawlak M, Sauer M, Asan E, Rothemund S, Winkler J, Prömel S, Nagel G, Langenhan T, Kittel RJ. Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons. Elife. 2017;6. pii: e28360.
  • Windholz J, Kovacs P, Schlicke M, Franke C, Mahajan A, Morris AP, Lemke JR, Klammt J, Kiess W, Schöneberg T, Pfäffle R, Körner A. Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children. J Pediatr Endocrinol Metab. 2017; 30: 507-15.


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2016

  • Brüser A, Schulz A, Rothemund S, Ricken A, Calebiro D, Kleinau G, Schöneberg T. The activation mechanism of glycoprotein hormone receptors with implications in the cause and therapy of endocrine diseases. J Biol Chem. 2016;291:508-20.
  • Fischer L, Wilde C, Schöneberg T, Liebscher IFunctional relevance of naturally occurring mutations in adhesion G protein-coupled receptor ADGRD1 (GPR133). BMC Genomics. 2016; 17: 609.
  • Jäger E, Schulz ALede V, Lin CC, Schöneberg TLeDuc D. Dendritic cells regulate GPR34 through mitogenic signals and undergo apoptosis in absence. J Immunol. 2016;196:2504-13
  • Kovacs P, Schöneberg T. The Relevance of Genomic Signatures at Adhesion GPCR Loci in Humans. Handb Exp Pharmacol. 2016; 234: 179-217.
  • Lede V, Franke C, Meusel A, Teupser D, Ricken A, Thiery J, Schiller J, Huster D, Schöneberg T, Schulz A. Severe Atherosclerosis and Hypercholesterolemia in Mice Lacking Both the Melanocortin Type 4 Receptor and Low Density Lipoprotein Receptor. PLoS One. 2016; 11:e0167888.
  • Le Duc, Schöneberg T. Adaptation to nocturnality - learning from avian genomes. Bioessays. 2016; 38: 694-703. 
  • Liebscher I, Schöneberg T. Tethered Agonism: A Common Activation Mechanism of Adhesion GPCRs. Handb Exp Pharmacol. 2016; 234: 111-25.
  • Merkwitz C, Blaschuk O, Eplinius F, Winkler J, Prömel S, Schulz A, Ricken A. A simple method for inducing estrous cycle stage-specific morphological changes in the vaginal epithelium of immature female mice. Lab Anim. 2016; 50: 344-53.
  • Merkwitz C, Blaschuk O, Schulz A, Ricken AM. Comments on Methods to Suppress Endogenous β-Galactosidase Activity in Mouse Tissues Expressing the LacZ Reporter Gene. J Histochem Cytochem. 2016; 64: 579-86.
  • Schöneberg T, Kleinau G, Brüser A. What are they waiting for? - Tethered agonism in G protein-coupled receptors. Pharmacol Res. 2016;108:9-15.
  • Prömel S, Fiedler F, Binder C, Winkler J, Schöneberg T, Thor D. Deciphering and modulating G protein signalling in C. elegans using the DREADD technology. Sci Rep. 2016; 6: 28901.
  • Stäubert C, Krakowsky R, Bhuiyan H, Witek B, Lindahl A, Broom O, Nordström A. Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells. Med Oncol. 2016;33:6. 
  • Strutt D, Schnabel R, Fiedler F, Prömel S. Adhesion GPCRs Govern Polarity of Epithelia and Cell Migration. Handb Exp Pharmacol. 2016; 234: 249-74.
  • Voiculescu SE, Duc DL, Roșca AE, Zeca V, Chiţimuș DM, Arsene AL, Drăgoi CM, Nicolae AC, Zăgrean L, Schöneberg T, Zăgrean AM. Behavioral and molecular effects of prenatal continuous light exposure in the adult rat. Brain Res. 2016; 1650: 51-59.
  • Wilde CFischer LLede VKirchberger J, Rothemund S, Schöneberg TLiebscher I. The constitutive activity of the adhesion GPCR GPR114/ADGRG5 is mediated by its tethered agonist. FASEB J. 2016;30:666-73.
  • Winkler J, Prömel S. The adhesion GPCR latrophilin - a novel signaling cascade in oriented cell division and anterior-posterior polarity. Worm. 2016; 5:e1170274. doi: 10.1080/21624054.2016.1170274.

 

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2015

  • Cöster M, Biebermann H, Schöneberg T, Stäubert C. Evolutionary Conservation of 3-Iodothyronamine as an Agonist at the Trace Amine-Associated Receptor 1. Eur Thyroid J. 2015;4: 9-20.
  • Demberg LM, Rothemund S, Schöneberg T, Liebscher I. Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG2. Biochem Biophys Res Commun. 2015;464:743-7
  • Dinter J, Mühlhaus J, Jacobi S, Wienchol CL, Cöster M, Meister J, Hoefig C, Müller A, Koehrle J, Grüters A, Krude H, Mittag J, Schöneberg T, Kleinau G, Biebermann H. 3-iodothyronamine differentially modulates alpha-2A adrenergic receptor-mediated signaling. J Mol Endocrinol. 2015;54:205-16.
  • Dinter J, Khajavi N, Mühlhaus J, Wienchol CL, Cöster M, Hermsdorf T, Stäubert C, Köhrle J, Schöneberg T, Kleinau G, Mergler S, Biebermann H. The multitarget ligand 3-iodothyronamine modulates beta-adrinergic receptor 2 signaling. Eur Thyroid J. 2015;4(Suppl 1):21-9
  • Dinter J, Mühlhaus J, Wienchol CL, Yi CX, Nürnberg D, Morin S, Grüters A, Köhrle J, Schöneberg T, Tschöp M, Krude H, Kleinau G, Biebermann H. Inverse agonistic actoin of 3-iodothyronamine at the human trace amine-associated receptor 5. PLoS One. 2015;10:e0117774.
  • Hamann J, Aust G, Arac D, Engel FB, Formstone C, Frederiksson R, Hall RA, Harty BL, Kirchhoff C, Knapp B, Krishnan A, Liebscher I, Lin HH, Martinelli DC, Monk KR, Peeters MC, Piao X, Prömel S, Schöneberg T, Schwartz TW, Singer K, Stacey M, Ushkaryov YA, Vallon M, Wolfrum U, Wright MW, Xu L, Langenhan T, Schiöth HB. International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. Pharmacol Rev. 2015;67:338-67.
  • Kloos M, Brüser A, Kirchberger J, Schöneberg T, Sträter N. Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation. Biochem J. 2015;469:421-32.
  • Le Duc D, Renaud G, Krishnan A, Almen MS, Huynen L, Prohaska SJ, Ongyerth M, Bitarello BD, Schiöth HB, Hofreiter M, Stadler PF, Prüfer K, Lambert D, Kelso J, Schöneberg T. Kiwi genome provides insights into evolution of a nocturnal lifestyle. Genome Biol. 2015;16:147.
  • Le Duc D, Spataru A, Ceanga M, Zagrean L, Schöneberg T, Toescu EC, Zagrean AM. Developmental exposure to ethanol increases the neuronal vulnerability to oxygen-glucose deprivation in cerebellar granule cell cultures. Brain Res. 2015;1614:1-13.
  • Liebscher I, Monk KR, Schöneberg T. How to wake a giant. Oncotarget. 2015;6:23038-9.
  • Liu X, Weidle K, Schröck K, Tönjes A, Schleinitz D, Breitfeld J, Stumvoll M, Böttcher Y, Schöneberg T, Kovacs P. Signatures of natural selection at the FTO (fat mass and obesity associated) locus in human populations. PLoS One. 2015;10:e0117093.
  • Monk KR, Hamann J, Langenhan T, Nijmeijer S, Schöneberg T, Liebscher I. Adhesion G-Protein Coupled Receptors: From In Vitro Pharmacology to In Vivo Mechanisms. Mol Pharmacol. 2015;88:617-23
  • Müller A, Winkler J, Fiedler F, Sastradihardja T, Binder C, Schnabel R, Kungel J, Rothemund S, Hennig C, Schöneberg T, Prömel S. Oriented Cell Division in the C. elegans Embryo Is Coordinated by G-Protein Signaling Dependent on the Adhesion GPCR LAT-1. PLoS Genet. 2015;11:e1005624.
  • Petersen SC, Luo R, Liebscher I, Giera S, Jeong SJ, Mogha A, Ghidinelli M, Feltri ML, Schöneberg T, Piao X, Monk KR. The adhesion GPCR GPR126 has distinct, domain-dependent functions in Schwann cell development mediated by interaction with laminin-211. Neuron. 2015;85:755-69.
  • Preissler J, Grosche A, Lede V, Le Duc D, Krügel K, Matyash V, Szulzewsky F, Kallendrusch S, Immig K, Kettenmann H, Bechmann I, Schöneberg T, Schulz A. Altered microglial phagocytosis in GPR34-deficient mice. Glia. 2015;63:206-15.
  • Schöneberg T, Liebscher I, Luo R, Monk KR, Piao X. Tethered agonists: a new mechanism underlying adhesion G protein-coupled receptor activation. J Recept Signal Transduct R. 2015;35:220-3.
  • Stäubert C, Broom OJ, Nordström A. Hydroxycarboxylic acid receptors are essential for breast cancer cells to control their lipid/fatty acid metabolism. Oncotarget. 2015;6:19706-20.
  • Stäubert C, Bhuiyan H, Lindahl A, Broom OJ, Zhu Y, Islam S, Linnarsson S, Lehtiö J, Nordström A. Rewired metabolism in drug-resistant leukemia cells: a metabolic switch hallmarked by reduced dependence on exogenous glutamine. J Biol Chem. 2015;290:8348-59


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2014

  • Busse K, Strotmann R, Strecker K, Wegner F, Devanathan V, Gohla A, Schöneberg T, Schwarz J. Adaptive gene regulation in the Striatum of RGS9-deficient mice. PLoS One. 2014;9:e92605.
  • Heyne HOLautenschläger S, Nelson R, Besnier F, Rotival M, Cagan A, Kozhemyakina R, Plyusnina IZ, Trut L, Carlborg Ö, Petretto E, Kruglyak L, Pääabo S, Schöneberg T, Albert FW. Genetic influences on braine gene expression in rats selected for tameness and aggression. Genetics. 2014;198:1277-90.
  • Kloos M, Brüser A, Kirchberger J, Schöneberg T, Sträter N. Crystallization and preliminary crystallographic analysis of human muscle phosphofructokinase, the main regulator of glycolysis. Acta Crystallogr F Struct Biol Commun. 2014;70:578-82.
  • Liebscher I, Ackley B, Araç D, Ariestanti DM, Aust G, Bae BI, Bista BR, Bridges JP, Duman JG, Engel FB, Giera S, Goffinet AM, Hall RA, Hamann J, Hartmann N, Lin HH, Liu M, Luo R, Mogha A, Monk KR, Peeters MC, Prömel S, Ressl S, Schiöth HB, Sigoillot SM, Song H, Talbot WS, Tall GG, White JP, Wolfrum U, Xu L, Piao X. New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors. Ann N Y Acad Sci. 2014; 1333:43-64.
  • Liebscher I, Schön J, Petersen SC, Fischer L, Auerbach N, Demberg LM, Mogha A, Cöster M, Simon KU, Rothemund S, Monk KR, Schöneberg T. A tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR 133. Cell Rep. 2014;9:2018-26.
  • Meister J, Le Duc D, Ricken A, Burkhardt R, Thiery J, Pfannkuche H, Polte T, Grosse J, Schöneberg T, Schulz A. The G protein-coupled receptor P2Y14 influences insulin release and smooth muscle function in mice. J Biol Chem. 2014;289:23353-66.


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2013

  • Guernsey MW, Ritscher L, Miller MA, Smith DA, Schöneberg T, Shapiro MD. A Val85Met mutation in Melanocortin-1 receptor is associated with reductions in eumelanic pigmentation and cell surface expression in domestic rock pigeons (Columbia livia). PLoS One. 2013 Aug 15;8:e74475.
  • Liebscher I, Schöneberg T, Prömel S. Progress in demystification of adhesion GPCR. Biol Chem. 2013;394:937-50.
  • Merkwitz C, Blaschuk OW, Schulz A, Lochhead P, Meister J, Ehrlich A, Ricken AM. The ductal origin of structural and functional heterogeneity between pancreatic islands. Prog Histochem Cytochem. 2013;48:103-40.
  • Mogha A, Benesh AE, Patra C, Engel FB, Schöneberg T, Liebscher I, Monk KR. Gpr126 functions in Schwann cells to control differentiation and myelination via G-protein activation. J Neurosci. 2013;33:17976-85.
  • Prado-Martinez J, Hernando-Herraez I, Lorente-Galdos B, Dabad M, Ramirez O, Baeza-Delgado C, Morcillo-Suarez C, Alkan C, Hormozdiari F, Raineri E, Estellé J, Fernandez-Callejo M, Valles M, Ritscher L, Schöneberg T, de la Calle-Mustienes E, Casillas S, Rubio-Acero R, Melé M, Engelken J, Caceres M, Gomez-Skarmeta JL, Gut M, Bertranpetit J, Gut IG, Abello T, Eichler EE, Mingarro I, Lalueza-Fox C, Navarro A, Marques-Bonet T. The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild. BMC Genomics. 2013;14:363.
  • Prömel S, Langenhan T, Araç D. Matching structure with function: the GAIN domain of Adhesion-GPCR and PKD1-like proteins. Trends Pharmacol Sci. 2013; 34: 470-8.
  • Schmidt P, Ritscher L, Dong EN, Hermsdorf T, Cöster M, Wittkopf D, Meiler J, Schöneberg T. Identification of determinants required for agonistic and inverse agonistic ligand properties at the ADP receptor P2Y12. Mol Pharmacol. 2013;83:256-66.
  • Schöneberg T, Kloos M, Brüser A, Kirchberger J, Sträter N. Structure and allosteric regulation of eukaryotic 6-phosphofructokinases. Biol Chem. 2013; 394: 977-93.
  • Stäubert C, Bohnekamp J, Schöneberg T. Determinants involved in subtype-specific functions of rat trace amine-associated receptors 1 and 4. Br J Pharmacol. 2013;168:1266-78.


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2012

  • Araç D, Aust G, Calebiro D, Engel FB, Formstone C, Goffinet A, Hamann J, Kittel RJ, Liebscher I, Lin HH, Monk KR, Petrenko A, Piao X, Prömel S, Schiöth HB, Schwartz TW, Stacey M, Ushkaryov YA, Wobus M, Wolfrum U, Xu L, Langenhan T. Dissecting signaling and functions of adhesion G protein-coupled receptors. Ann N Y Acad Sci. 2012; 1276: 1-25.
  • Boeselt I, Tramma D, Kalamitsou S, Niemeyer T, Nykänen P, Gräf KJ, Krude H, Marenzi KS, Di Candia S, Schöneberg T, Schulz A. Functional characterization of novel loss-of-function mutations in the vasopressin type 2 receptor gene causing nephrogenic diabetes insipidus. Nephrol Dial Transplant. 2012; 27:1521-8.
  • Brüser A, Kirchberger J, Kloos M, Sträter N, Schöneberg T. Functional linkage of adenine nucleotide binding sites in the mammalian muscle 6-phosphofructokinase. JBC. 2012; 287: 17546-53.
  • Brüser A, Kirchberger J, Schöneberg T. Altered allosteric regulation of muscle 6-phosphofructokinase causes Tarui disease. Biochem Biophys Res Commun. 2012; 427: 133-137.
  • Cöster M, Wittkopf D, Kreuchwig A, Kleinau G, Thor D, Krause G, Schöneberg T. Using ortholog sequence data to predict the functional relevance of mutations in G-protein-coupled receptors. FASEB J. 2012; 26: 3273-81.
  • Gregory AP, Dendrou CA, Attfield KE, Haghikia A, Xifara DK, Butter F, Poschmann G, Kaur G, Lambert L, Leach OA, Prömel S, Punwani D, Felce JH, Davis SJ, Gold R, Nielsen FC, Siegel RM, Mann M, Bell JI, McVean G, Fugger L. TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis. Nature. 2012; 488:508-11.
  • Hu J, Thor D, Zhou Y, Liu T, Wang Y, McMillin SM, Mistry R, Challiss RA, Costanzi S, Wess J. Structural aspects of M₃ muscarinic acetylcholine receptor dimer formation and activation. FASEB J. 2012; 26: 604-16.
  • Melchior C, Schulz A, Windholz J, Kiess W, Schöneberg T, Körner A. Clinical and functional relevance of melanocortin-4 receptor variants in obese German children. Horm Res Paediatr. 2012;78:237-46.
  • Prömel S, Frickenhaus M, Hughes S, Mestek L, Staunton D, Woollard A, Vakonakis I, Schöneberg T, Schnabel R, Russ AP, Langenhan T. The GPS motif is a molecular switch for bimodal activities of adhesion class G protein-coupled receptors. Cell Rep. 2012; 2: 321-31.
  • Prömel S, Waller-Evans H, Dixon J, Zahn D, Colledge WH, Doran J, Carlton MB, Grosse J, Schöneberg T, Russ AP, Langenhan T. Characterization and functional study of a cluster of four highly conserved orphan adhesion-GPCR in mouse. Dev Dyn. 2012; 241:1591-602.
  • Ritscher L, Engemaier E, Stäubert C, Liebscher I, Schmidt P, Hermsdorf T, Römpler H, Schulz A, Schöneberg T. The ligand specificity of the G-protein-coupled receptor GPR34. Biochem J. 2012; 443:841-50.
  • Rossol M, Pierer M, Raulien N, Quandt D, Meusch U, Rothe K, Schubert K, Schöneberg T, Schaefer M, Krügel U, Smajilovic S, Bräuner-Osborne H, Baerwald C, Wagner U. Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors. Nat Commun. 2012;3:1329.
  • Tarnow P, Rediger A, Schulz A, Grüters A, Biebermann H. Identification of the translation start site of the human melanocortin 3 receptor. Obes Facts. 2012;5:45-51.


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2011

  • Albert FW, Hodges E, Jensen JD, Besnier F, Xuan Z, Rooks M, Bhattacharjee A, Brizuela L, Good JM, Green RE, Burbano H, Plyusnina IZ, Trut L, Andersson L, Schöneberg T, Carlborg Ö, Hannon GJ, Pääbo S. Targeted resequencing of a genomic region influencing tameness and aggression reveals multiple signals of positive selection. Heredity. 2011;107:205-14.
  • Bohnekamp J, Schöneberg T. The cell-adhesion receptor GPR133 couples to the G proteins. JBC. 2011;286:41912-6.
  • Engel KM, Schröck K, Teupser D, Holdt LM, Tönjes A, Kern M, Dietrich K, Kovacs P, Krügel U, Scheidt HA, Schiller J, Huster D, Brockmann GA, Augustin M, Thiery J, Blüher M, Stumvoll M, Schöneberg T, Schulz A. Reduced food intake and body weight in mice deficient for the G protein-coupled receptor GPR82. PLoS One. 2011;6:e29400.
  • Frenzel J, Gessner C, Sandvoss T, Hammerschmidt S, Schellenberger W, Sack U, Eschrich K, Wirtz H. Outcome Prediction in Pneumonia Induced ALI/ARDS by Clinical Features and Peptide Patterns of BALF Determined by Mass Spectrometry. PLoS One. 2011;6:e25544.
  • Kleinau G, Pratzka J, Nürnberg D, Grüters A, Führer-Sakel D, Krude H, Köhrle J, Schöneberg T, Biebermann H. Differential Modulation of Beta-Adrenergic Receptor Signaling by Trace Amine-Associated Receptor 1 Agonists. PLoS One. 2011;6:e27073.
  • Lakner J, Seyer C, Hermsdorf T, Schöneberg T. Characterization of the expression, promoter activity and and molecular architecture of fibin. BMC Biochem. 2011;12:26.
  • Liebscher I, Müller U, Teupser D, Engemaier E, Engel KM, Ritscher L, Thor D, Sangkuhl K, Ricken A, Wurm A, Piehler D, Schmutzler S, Fuhrmann H, Albert FW, Reichenbach A, Thiery J, Schöneberg T, Schulz A. Altered immune response in mice deficient for the G protein-coupled receptor GPR34. J Biol Chem. 2011;286:2101-10.
  • Rediger I, Piechowski CL, YI CX, Tarnow P, Strotmann R, Grueters A, Krude H, Schöneberg T, Tschoep MH, Kleinau G, Biebermann H. Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin- and melanocortin-3 receptors. JBC. 2011;286:39623-31.
  • Remmerbach TW, Maurer K, Janke S, Schellenberger W, Eschrich K, Bertolini J, Hofmann H, Rupf S. Oral brush biopsy analysis by matrix assisted laser desorption/ionisation-time of flight mass spectrometry profiling - a pilot study. Oral Oncol. 2011;47:278-81.
  • Sträter N, Marek S, Kuettner EB, Kloos M, Keim A, Brüser A, Kirchberger J, Schöneberg T. Molecular architecture and structural basis of allosteric regulation of eukaryotic phosphofructokinases. FASEB J. 2011;25:89-98.
  • Strotmann R, Schröck IK, Böselt I, Stäubert C, Russ A, Schöneberg T. Evolution of GPCR: change and continuity. Mol Cell Endocrinol. 2011;331:170-8.


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2010

  • Bohnekamp J, Böselt I, Saalbach A, Tönjes A, Kovacs P, Biebermann H, Manvelyan HM, Polte T, Gasperikova D, Lkhagvasuren S, Baier L, Stumvoll M, Römpler H, Schöneberg T (2010) Involvement of the chemokine-like receptor GPR33 in innate immunitiy. Biochem Biophys Res Commun 396:272-7 .
  • Hofreiter M, Schöneberg T (2010) The genetic and evolutionary basis of colour variation in verteberates. Cell Mol Life Sci 67:2591-603 .
  • Kretschmer D, Gleske A-K, Rautenberg M, Wang R, Köberle M, Erwin Bohn, Schöneberg T, Rabiet M-J, Boulay F, Klebanoff SJ, van Kessel KA, van Strijp JA, Otto M, Peschel A (2010) Human formyl peptide receptor 2 (FPR2/ALX) senses highly pathogenic staphylococcus aureus. Cell Host Microbe 7:463-473.
  • Rosenblum EB, Römpler H, Schöneberg T, Hoekstra HE (2010) Molecular and functional basis of phenotypic convergence in white lizards at White Sands. Proc Natl Acad Sci U S A 107:2113-7 .
  • Schöneberg T, Schröck K, Stäubert C, Russ A (2010) The evolution of the repertoire and structure of G protein-coupled receptors, in: G Protein-Coupled Receptors", Eds S. Siehler and G. Milligan.
  • Schöneberg T, Illes P, Burnstock G (2010) The German Research Unit "Neuronal and glial P2 receptors; molecular basis and functional significance". Purinergic Signal. 2010 6:285-7.
  • Stäubert C, Böselt I, Bohnekamp J, Römpler H, Enard W, Schöneberg T (2010) Structural and functional evolution of the trace amine-associated receptors TAAR3, TAAR4 and TAAR5 in primates. PLoS One 5:e11133 .
  • Strotmann R, Semtner M, Kepura F, Plant TD, Schöneberg T (2010) Interdomain Interactions Control Ca2+-Dependent Potentiation in the Cation Channel TRPV4. PLoS One 5: e10580 .
  • Turner LM, Young AR, Römpler H, Schöneberg T, Phelps SM, Hoekstra HE (2010) Monogamy evolves through multiple mechanisms: Evidence from V1aR in deer mice. Mol Biol Evol 27:1269-78 .
  • Wurm A, Lipp S, Pannicke T, Linnertz R, Krügel U, Schulz A, Färber K, Zahn D, Grosse J, Wiedemann P, Chen J, Schöneberg T, Illes P, Reichenbach A, Bringmann A (2010) Endogenous purinergic signaling is required for osmotic volume regulation of retinal glial cells. J Neurochem 112:1261-1272 .


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2009

  • Albert FW, Carlborg O, Plyusnina I, Besnier F, Hedwig D, Lautenschläger S, Lorenz D, McIntosh J, Neumann C, Richter H, Zeising C, Kozhemyakina R, Shchepina O, Kratzsch J, Trut L, Teupser D, Thiery J, Schöneberg T, Andersson L, Pääbo S (2009) Genetic architecture of tameness in a rat model of animal domestication. Genetics 182:541-54 .
  • Benjamin S, Radermacher M, Kirchberger J, Schöneberg T, Edelmann A, Ruiz T (2009) 3D structure of phosphofructokinase from Pichia pastoris: Localization of the novel gamma-subunits. J Struct Biol 168:1599-614 .
  • Böselt I, Römpler H, Hermsdorf T, Thor D, Busch W, Schulz A, Schöneberg T (2009) Involvement of the V2 vasopressin receptor in adaption to limited water supply. PLoS One 4:e5573 .
  • Danielyan L, Schäfer R, Schulz A, Ladewig T, Lourhmati A, Buadze M, Schmitt AL, Verleysdonk S, Kabisch D, Koeppen K, Siegel G, Proksch B, Kluba T, Eckert A, Köhle C, Schöneberg T, Northoff H, Schwab M, Gleiter CH (2009) Survival, neuron-like differentiation and functionality of mesenchymal stem cels in neurotoxic environment: the critical role of erythropoietin. Cell Death Differ 16:1599-614 .
  • Hofreiter M, Römpler H (2009) Polymerase chain reaction: A blessing and a curse for ancient deoxyribonucleic acid research. In: Bustin SA: The PCR Revolution - Basic Technologies and Applications. Cambridge: 284-300.
  • Koch D, Sakurai M, Hummitzsch K, Hermsdorf T, Erdmann S, Schwalbe S, Stolzenburg JU, Spanel-Borowski K, Ricken AM (2009) KIT variants in bovine ovarian cells and corpus luteum. Growth Factors 27:100-113 .
  • Melchior C, Kiess W, Dittrich K, Schulz A, Schöneberg T, Körner A (2009) Slim despite a genetic predisposition for obesity - influence of environmental factors as a chance? A case report. Dtsch Med Wochenschr 134:1047-50 .
  • Sandrock M, Schulz A, Merkwitz C, Schöneberg T, Spanel-Borowski K, Ricken A (2009) Reduction in corpora lutea number in obese melanocortin-4 receptor-deficient mice. Reprod Biol Endocrinol 7:24 .
  • Steiner CC, Römpler H, Boettger LM, Schöneberg T, Hoekstra HE (2009) The genetic basis of phenotypic convergence in beach mice: similar pigment patterns but different genes. Mol Biol Evol 26:35-45 .
  • Thor D, Le Duc D, Strotmann R, Schöneberg T (2009) Luciferase activity under direct ligand-dependent control of a muscarinic acetylcholine receptor. BMC Biotechnol 18:9;46.


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2008

  • Albert FW, Shchepina O, Winter C, Römpler H, Teupser D, Palme R, Ceglarek U, Kratzsch J, Sohr R, Trut LN, Thiery J, Morgenstern R, Plyusnina IZ, Schöneberg T, Pääbo S (2008) Phenotypic differences in behavior, physiology and neurochemistry between rats selected for tameness and for defensive aggression towards humans. Horm Behav 53:413-21 .
  • Bryk J, Hardouin E, Pugach I, Hughes D, Strotmann R, Stoneking M, Myles S (2008) Positive selection in East Asians for an EDAR allele that enhances NF-kappaB activation. PLoS One 3:2209ff .
  • Erdmann S, Ricken AM, Hummitzsch K, Merkwitz C, Schliebe N, Gaunitz F, Strotmann R, Spanel-Borowski K (2008) Inflammatory cytokines increase extracellular procathepsin D in permanent and primary endothelial cell cultures. Eur. J. Cell Biol 87:311-23 .
  • Hollenbach M, Hintersdorf A, Huse K, Sack U, Bigl M, Groth M, Santel T, Buchold M, Lindner I, Otto A, Sicker D, Schellenberger W, Almendinger J, Pustowoit B, Birkenmeyer C, Platzer M, Oerlecke I, Hemdan N, Birkemeier G (2008) Ethyl pyruvate and ethyl lactate down-regulate the production of pro-inflammatory cytokines and modulate expression of immune receptors. Biochem Pharmacol 76:631-644 .
  • Hughes DA, Tang K, Strotmann R, Schöneberg T, Prenen J, Nilius B, Stoneking M (2008) Parallel selection on TRPV6 in human populations. PLoS One 3:e1686 .
  • Klinke T, Rump A, Ponisch R, Schellenberger W, Muller EC, Otto A, Klimm W, Kriegel TM (2008)
    Identification and characterization of CaApe2 - a neutral arginine/alanine/leucine-specific metallo-aminopeptidase from Candida albicans. FEMS Yeast Res 8:858-869 .
  • Santel T, Pflug G, Hemdan NY, Schäfer A, Hollenbach M, Buchold M, Hintersdorf A, Lindner I, Otto A, Bigl M, Oerlecke I, Hutschenreuter A, Sack U, Huse K, Groth M, Birkemeyer C, Schellenberger W, Gebhardt R, Platzer M, Weiss T, Vijayalakshmi MA, Krüger M, Birkenmeier G (2008) Curcumin inhibits glyoxalase 1: a possible link to its anti-inflammatory and anti-tumor activity. PLoS ONE 3:3508-3508 .
  • Schliebe N, Strotmann R, Busse K, Mitschke D, Biebermann H, Schomburg L, Köhrle J, Bär J, Römpler H, Wess J, Sangkuhl K (2008) V2 vasopressin receptor deficiency causes changes in expression and function of renal and hypothalamic components involved in electrolyte and water homeostasis. Am J Physiol Renal Physiol 295:F1177-90 .
  • Schöneberg T (2008) Tolerance and Desensitization. In: Offermann S, Rosenthal W: Encyclopedia of Molecular Pharmacology. 2nd ed. Berlin; Heidelberg: 1203-1207.
  • Sensken SC, Stäubert C, Keul P, Levkau B, Schöneberg T, Gräler MH (2008) Selective activation of G alpha i mediated signalling of S1P3 by FTY720-phosphate. Cell Signal 20:1125-33.


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2007

  • Benjamin S, Radermacher M, Bär J, Edelmann A, Ruiz T. (2007) Structures of S. pombe phosphofructokinase in the F6P-bound and ATP-bound states. J Struct Biol. 159: 498-506
  • Lalueza-Fox C, Römpler H, Caramelli D, Stäubert C, Catalano G, Hughes D, Rohland N, Pilli E, Longo L, Condemi S, de la Rasilla M, Fortea J, Rosas A, Stoneking M, Schöneberg T, Bertranpetit J, Hofreiter M (2007) A melanocortin 1 receptor allele suggests varying pigmentation among Neanderthals. Science 318:1453-5
  • Schöneberg T, Hermsdorf T, Engemaier E, Engel K, Liebscher I, Thor D, Zierau K, Römpler H, Schulz A (2007) Structural and functional evolution of the P2Y12-like receptor group. Purinergic Signal 3:255-268
  • Stäubert C, Tarnow P, Pitra C, Gudermann T, Grüters A, Schöneberg T, Biebermann H, Römpler H (2007) Evolutionary aspects in evaluating mutations in the melanocortin type 4 receptor. Endocrinology 148: 4642-8
  • Schöneberg T (2007) Pharmakologie. In: Therapie in der Kinder- und Jugendmedizin. (Eds. Kiess W, Merkenschlager A, Pfäffle R, Siekmeyer K), Elsevier: 4-25
  • Strotmann R, Schöneberg T, Römpler H. (2007) Pharmakotherapie. In: Therapie in der Kinder- und Jugendmedizin. (Eds. Kiess W, Merkenschlager A, Pfäffle R, Siekmeyer K), Elsevier: 27-139
  • Barcena M, Radermacher M, Bär J, Kopperschläger G, Ruiz T. (2007) The structure of the ATP-bound state of S. cerevisiae phosphofructokinase determined by cryo-electron microscopy. J Struct Biol. 159: 135-143
  • Römpler H, Stäubert C, Thor D, Schulz A, Hofreiter M, Schöneberg T (2007) G protein–coupled time travel: Evolutionary aspects of GPCR research. Mol Interv 7: 17-27
  • Plant TD, Strotmann R (2007) TRPV4: A Multifunctional Nonselective Cation Channel with Complex Regulation. In: TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades (Ed. Liedtke WB) CRC Press: 125-140
  • Welt K, Weiss J, Martin R, Hermsdorf T, Drews S, Fitzl G (2007) Ginkgo biloba extract protects rat kidney from diabetic and hypoxic damage. Phytomedicine 14:196-203
  • Tanneberger K, Kirchberger J, Bär J, Schellenberger W, Rothemund S, Kamprad M, Otto H, Schöneberg T, Edelmann A (2007) A novel form of 6-phosphofructokinase: Identification and functional relevance of a third type of subunit in Pichia pastoris. J Biol Chem. 282: 23687-97
  • Friedrichs C, Rodloff AC, Chhatwal GS, Schellenberger W, Eschrich K. (2007) Rapid identification of viridans streptococci by mass-spectrometric discrimination. J Clin Microbiol. 45: 2392-7
  • Schöneberg T, Hofreiter M, Schulz A, Römpler H (2007) Learning from the past: evolution of GPCR functions. Trends Pharmacol Sci 28: 117-21
  • Merten N, Lindner D, Rabe N, Römpler H, Mörl K, Schöneberg T, Beck-Sickinger AG (2007) Receptor Subtype-specific Docking of Asp6.59 with C-terminal Arginine Residues in Y Receptor Ligands. J Biol Chem 282: 7543-7551
  • Plant TD, Strotmann R (2007) TRPV4. Handb Exp Pharmacol: 189-205
  • Schmidt H, Kunerth S, Wilms C, Strotmann R, Eilers J. (2007) Spino-dendritic crosstalk in rodent Purkinje neurons mediated by endogenous Ca2+-binding proteins. J Physiol 581: 619-629.


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2006

  • Schulz A, Römpler H, Mitschke D, Thor D, Schliebe N, Hermsdorf T, Strotmann R, Sangkuhl K, Schöneberg T (2006) Molecular basis and features of nephrogenic diabetes insipidus. Expert Rev Endocrinol Metab 1: 727-741.
  • Römpler H, Rohland N, Lalueza-Fox C, Willerslev E, Kuznetsova T, Rabeder G, Bertranpetit J, Schöneberg T, Hofreiter M (2006) Nuclear gene indicates coat-color polymorphism in mammoths. Science 313: 62.
  • Römpler H, Dear PH, Krause J, Meyer M, Rohland N, Schöneberg T, Spriggs H, Stiller M, Hofreiter M (2006) Multiplex amplification of ancient DNA. Nature Protocols 1: 720-8.
  • Grosse J, Tarnow P, Römpler H, Schneider B, Sedlmeier R, Nehls M, Wattler S, Schöneberg T, Biebermann H, Augustin M (2006) N-Ethyl N-nitrosourea-based generation of mouse models for mutant G-protein-coupled receptors. Physiol Genomics 26: 209-217.
  • Römpler H, Yu HT, Arnoldt A, Orth A, Schöneberg T (2006) Functional consequences of naturally occurring DRY motif variants in the mammalian chemoattractant receptor GPR33. Genomics 87: 724-32.
  • Zaki M, Schöneberg T, Al Ajrawi T, Al Said AN, Sangkuhl K, Römpler H (2006) Nephrogenic diabetes insipidus, thiazide treatment and renal cell carcinoma: a case report. Nephrol Dial Transplant 21: 1082-6.
  • Schöneberg T (2006) Endo- und parakrine Regulation der Gonadenfunktion. In "Molekularmedizinische Grundlagen von para- und autokrinen Regulationsstörungen", Ed. D. Ganten K. Ruckpaul, Springer Verlag, 581-605.
  • Engemaier E, Römpler H, Schöneberg T, Schulz A (2006) Genomic and supragenomic structure of the nucleotide-like G-protein-coupled receptor GPR34. Genomics 87: 254-64.

 
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2005

  • Edelmann A, Krüger M, Schmid J (2005) Genetic relationship between human and animal isolates of Candida albicans. J. Clin. Microbiol. 43:6164-6.
  • Römpler H, Schulz A, Pitra C, Coop G, Przeworski M, Pääbo S, Schöneberg T. (2005) The rise and fall of the chemoattractant receptor GPR33. J Biol Chem. Sep 2;280(35):31068-75.
  • Sangkuhl K, Römpler H, Busch W, Karges B, Schöneberg T. (2005) Nephrogenic diabetes insipidus caused by mutation of Tyr205: a key residue of V2 vasopressin receptor function. Hum Mutat. 2005 May;25(5):505
  • Richter W, Hermsdorf T, Dettmer D (2005) Renaturation of the catalytic domain of PDE4A expressed in Escherichia coli as inclusion bodies. Methods Mol Biol. 307:155-65.
  • Schöneberg T (2005) Krankheitsrelevante Mutationen in G-Protein-gekoppelten Rezeptoren. BIOforum 5: 28-30
  • Gerber M, Boettner A, Seidel B, Lammert A, Bär J, Schuster E, Thiery J, Kiess W, Kratzsch J. (2005) Serum resistin levels of obese and lean children and adolescents: biochemical analysis and clinical relevance. J Clin Endocrinol Metab. 90:4503-9.
  • Schöneberg T, Sangkuhl K, Römpler H, Schulz A (2005) Enzyme-linked immunosorbent assays as tools in studying interactions of G-protein-coupled receptors. In: G protein-coupled receptor-protein interactions. Eds S.R. George and B.F. O’Dowd. John Wiley & Sons. Inc., pp 257-277.


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2004

  • Bojarski, C., J. Weiske, T. Schöneberg, W. Schröder, J. Mankertz, J.D. Schulzke, P. Florian, M. Fromm, R. Tauber, and O. Huber (2004) The specific fates of tight junction proteins in apoptotic epithelial cells. J. Cell Sci. 117: 2097-2107.
  • Fleischmann BK, Duan Y, Fan Y, Schöneberg T, Ehlich A, Lenka N, Viatchenko-Karpinski S, Pott L, Hescheler J, Fakler B (2004) Differential subunit composition of the G protein-activated inward-rectifier potassium channel during cardiac development. J Clin Invest 114(7): 994-1001.
  • Fuchs S, Kapp T, Otto H, Schöneberg T, Franke P, Gust R, Schlüter AD (2004) A surface-modified dendrimer set for potential application as drug delivery vehicles: synthesis, in vitro toxicity, and intracellular localization. Chemistry 10(5): 1167-1192.
  • Gross P, Schöneberg T (2004) Rescue of protein mutants: why? Nephrol Dial Transplant 5: 1029-1032.
  • Sangkuhl K, Schulz A, Römpler H, Yun J, Wess J, Schöneberg T (2004) Aminoglycoside-mediated rescue of a disease-causing nonsense mutation in the V2 vasopressin receptor gene in vitro and in vivo. Hum Mol Genet 9: 893-903 http://hmg.oupjournals.org/cgi/content/full/13/9/893.
  • Schöneberg, T. (2004). Nephrogenic Diabetes Insipidus. In: The Encyclopedia of Endocrinology and Endocrine Diseases. Ed.: L. Martini Academic Press, San Diego, 651-654.
  • Schöneberg, T. (2004) In: Molecular Pharmacology - an Encyclopedic Reference. Eds. S. Offermanns and W. Rosenthal, Springer Verlag, 912-916
  • Schöneberg T (2004) Tolerance and desensitization. In: Offermanns S, Rosenthal W: Encyclopedic Reference of Molecular Pharmacology, Springer Verlag, Berlin pp. 913-916.
  • Schöneberg T, Schulz A, Biebermann H, Hermsdorf T, Rompler H, Sangkuhl K (2004) Mutant G-protein-coupled receptors as a cause of human diseases. Pharmacol Ther 104(3): 173-206.
  • Schwock, J., J. Kirchberger, A. Edelmann, T.M. Kriegel, and G. Kopperschläger (2004) Interaction of 6-phosphofructokinase with cytosolic proteins of Saccharomyces cerevisiae. Yeast 21, 483-494.
  • Welt K, Weiss J, Martin R, Dettmer D, Hermsdorf T, Asayama K, Meister S, Fitzl G (2004) Ultrastructural, immunohistochemical and biochemical investigations of the rat liver exposed to experimental diabetes und acute hypoxia with and without application of Ginkgo extract. Exp Toxicol Pathol 55(5): 331-345.


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2003

  • Niedernberg A, Blaukat A, Schöneberg T, Kostenis E (2003) Resolution of constitutive activity of the human S1P5 receptor in various biochemical and cellular assays. Brit. J. Pharmacol. 128: 481-493.
  • Schulz A, Schöneberg T (2003) The structural evolution of a P2Y-like G-protein-coupled receptor J. Biol. Chem. 278: 34998-35015.
  • Strotmann R, Schultz G, Plant TD (2003) Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site. J Biol Chem 278: 26541-9.
  • Jung S, Muhle A, Schaefer M, Strotmann R, Schultz G, Plant TD. (2003) Lanthanides potentiate TRPC5 currents by an action at extracellular sites close to the pore mouth. J Biol Chem. 278: 3562-71
  • Neuschafer-Rube F, Engemaier E, Koch S, Boer U, Püschel GP. (2003) Identification by site-directed mutagenesis of amino acids contributing to ligand-binding specificity or signal transduction properties of the human FP prostanoid receptor. Biochem J. 371: 443-9.
  • Ruiz T, Mechin I, Bär J, Rypniewsky W, Kopperschläger G, Radermacher M (2003) The 10.8-A structure of Saccharomyces cerevisiae phosphofructokinase determined by cryoelectron microscopy: localization of the putative fructose 6-phosphate binding sites. J. Struct. Biol. 143:124-134.
  • Tarnow P, Schöneberg T, Krude H, Grüters A, Biebermann H (2003) Mutationally induced disulfide bond formation within the third extracellular loop causes melanocortin 4 receptor inactivation in patients with obesity. J. Biol. Chem. 278: 48666-48673.


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